Dose-dependent inhibitory effect of IL-10 on autonomous BFU-E growth from PV cells and its abrogation by an anti-IL-10 antibody in patient HR. A total of 120 × 10³ PBMNC/mL were cultured in methylcellulose with medium alone, with increasing concentrations of IL-10, or with IL-10 plus a neutralizing antibody against IL-10. Colony growth was assessed after 14 days. Results represent the mean values ± standard deviation (SD) from triplicates. * Significant change from control with P value at least <.05.