Comparison of ABP-278 and ABP-276 amino terminal 248 amino acids with the actin-binding domains of other ABPs. Amino acids conserved in five or more members of the group are highlighted in bold. The group of ABPs includes: human β-spectrin (HSpec),34,Drosophilaspectrin (DrSpec),35 human dystrophin (HDys),37 chicken dystrophin (CDys),36 chicken -actinin (CAct),32,Dictyostelium -actinin (DAct),33,Dictyostelium gelation factor (DGF),31 human ABP-280,17chicken filamin protein (MCFil),47 and human ABP homologues ABP-276 and ABP-278.