Fig. 1.
Fig. 1. Comparison of partial RAMP and ZNF198 ORFs with the revised, completed ZNF198 protein and ZNF198/FGFR1 fusion product. This completed sequence contains the five atypical zinc fingers reported by Smedley et al9 and the proline repeats and potential acidic activation domain first reported by Xiao et al.8 The translocation therefore fuses the five zinc fingers and one complete proline repeat to the tyrosine kinase domain of FGFR1.

Comparison of partial RAMP and ZNF198 ORFs with the revised, completed ZNF198 protein and ZNF198/FGFR1 fusion product. This completed sequence contains the five atypical zinc fingers reported by Smedley et al9 and the proline repeats and potential acidic activation domain first reported by Xiao et al.8 The translocation therefore fuses the five zinc fingers and one complete proline repeat to the tyrosine kinase domain of FGFR1.

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