Effect of Fas triggering on bcr/abl expression (mRNA and protein) from a CML patient in chronic phase who had optimal response to IFN-α and showed in vitro susceptibility to Fas-mediated apoptosis. Quantitative RT-PCR: (A) densitometry and (B) agarose gel. (C) Immunoblotting of p210 from total BM cells. Fas triggering induced downregulation of p210, but not of bcr/abl mRNA.