Fig. 10.
Fig. 10. Mutant c-jun–containing 8226 cells are protected from anti–fas-induced DNA laddering but not from dexamethasone. Neo control (lanes A through D and I through K) and mutant c-jun–transduced 8226 cells (lanes E through H and L through N) were cultured in media for 20 hours (lanes A and E) or 48 hours (lanes I and L) or with increasing concentrations of anti-fas (0.1, 0.25, 0.5 μg/mL, lanes B through D and F through H) or with dexamethasone (10−6 mol/L and 2 × 10−6 mol/L, lanes J and K and M and N, respectively). DNA was then extracted and electrophoresed.

Mutant c-jun–containing 8226 cells are protected from anti–fas-induced DNA laddering but not from dexamethasone. Neo control (lanes A through D and I through K) and mutant c-jun–transduced 8226 cells (lanes E through H and L through N) were cultured in media for 20 hours (lanes A and E) or 48 hours (lanes I and L) or with increasing concentrations of anti-fas (0.1, 0.25, 0.5 μg/mL, lanes B through D and F through H) or with dexamethasone (10−6 mol/L and 2 × 10−6 mol/L, lanes J and K and M and N, respectively). DNA was then extracted and electrophoresed.

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