Kaplan-Meier analysis of survival. Group 1: 22 mice received 1 to 2 million fresh marrow cells. Group 2: 21 mice transplanted with 1 to 2 million marrow cells cultured in QBSF58 serum-free medium for 4 days, as was group 3, but not exposed to the CD adenoviral vector/5-FC. Group 3: 19 mice transplanted with 1 to 2 million marrow cells exposed to the CD adenoviral vector followed by 5-FC. Survival for each group was estimated by the Kaplan-Meier model. Log-rank test was used to check for equality of survival functions. Sixty-two mice were studied. Follow-up was 83.9 ± 43.4 days (mean ± SD), with a range of 4 to 145 days. Survival functions: Results are given as the mean ± SE, with the 95% confidence interval in parentheses. Group 1: 22 mice were transplanted and 19 survived (from 3 different experiments). Three died at day 6. Survival function: 86.4 ± 7.3 (63.4 to 95.4). Group 2: 21 mice were transplanted, 19 survived and 2 died at days 6 and 8 (2 different experiments). Survival: 90.5 ± 6.4 (67 to 97.5). Group 3: 19 mice were transplanted. Six died at days 4 (1 mouse), 6 (2 mice), 9 (2 mice), and 18 (1 mouse) (4 different experiments total). Survival: 68.4 ± 10.7 (42.8 to 84.4). Log-rank test: P = .16. There was no difference in survival among these 3 groups.