Fig. 4.
Effect of AM580 (RARα agonist), CD2019 (RARβ agonist), and CD437 (RARγ agonist) on CP chromogenic activity (A) and TF activity (B) in S-NB4 cells. Cells were cultured ATRA (10−6 mol/L) or synthetic retinoids (10−8mol/L) for 96 hours. (□), Untreated; (▪), treated. The results are the mean of at least three experiments. Statistical analysis as in Fig 1. *P < .05, **P < .01.
