Fig. 3.
Fig. 3. Southern analysis of tail DNA from hemizygous male and carrier female mice. Tail DNA from normal male (+/0), affected male (−/0), and carrier female (+/−) mice were digested withXba I and hybridized with (A) probe A and (B) probe B. The expected sizes of the bands were the same as those detected in the ES cell clones (see Fig 2).

Southern analysis of tail DNA from hemizygous male and carrier female mice. Tail DNA from normal male (+/0), affected male (−/0), and carrier female (+/−) mice were digested withXba I and hybridized with (A) probe A and (B) probe B. The expected sizes of the bands were the same as those detected in the ES cell clones (see Fig 2).

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