Effects of A3P5P on cAMP levels in washed human platelets (A) and in B10 cells (B). (A) (▧), Vehicle; (▧), PGE₁ 1 μmol/L; (▧), +ADP 5μmol/L; (▨), +ATPαS 100 μmol/L / ADP 5 μmol/L; (▪), + A3P5P 100 μmol/L / ADP 5 μmol/L; (▥), +A2P5P 100 μmol/L / ADP 5 μmol/L. (B) (▧), Vehicle; (▧), forskolin 1 μmol/L; (▧), +ADP 1 μmol/L; (▨), +ATPαS 100 μmol/L / ADP 1 μmol/L; (▪), +A3P5P 100 μmol/L / ADP 1 μmol/L; (▥), +A2P5P 100 μmol/L / ADP 1 μmol/L. Values are means (±SEM) from one experiment performed in triplicate, representative of three separate experiments giving identical results.