Fig. 5.
Fig. 5. (A) Alignment of anti-Rh(D) λ light chains to their nearest germline V and J genes and (B) alignment of the 10 Vλ germline genes used shows the use of a diverse set of variable region genes derived from multiple families. However, all of the clones use the identical Jλ gene segment. Nomenclature for the clones is similar to that for heavy chains but uses the letters J through S. The key is the same as that used in Fig2A. Genbank accession numbers for anti-Rh(D) λ light chains are listed in the Appendix.

(A) Alignment of anti-Rh(D) λ light chains to their nearest germline V and J genes and (B) alignment of the 10 Vλ germline genes used shows the use of a diverse set of variable region genes derived from multiple families. However, all of the clones use the identical Jλ gene segment. Nomenclature for the clones is similar to that for heavy chains but uses the letters J through S. The key is the same as that used in Fig2A. Genbank accession numbers for anti-Rh(D) λ light chains are listed in the Appendix.

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