Fig. 1.
Detection and identification of MMAC1/PTENmutations in primary lymphomas. (A) PCR/DGGE analysis ofMMAC1/PTEN exon 1 in 10 tumor samples. (B) Direct sequence analysis of the sample displaying an aberrant band pattern in (A). The partial sequence ladder shows a G → A transition, resulting in the substitution of Ser10 with Asn10.
