Fig. 3.
![Metastasis of MM cells within SCID-hu mice. SCID-hu mice were treated with irradiation (400 cGy), injected directly into the marrow cavity of the left fetal human bone implant with 5 × 104 ARH-77 MM cells, and killed 12 weeks later. H&E (original magnification × 100 [A] and × 400 [B]) and immunoperoxidase staining with anti-κ Ig Ab (original magnification × 100 [C] and × 1,000 [D]) of the right-sided human fetal bone marrow implant is shown.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/90/2/10.1182_blood.v90.2.754/4/bl_0023f3e.jpeg?Expires=1720288676&Signature=l9SHn6u2Z2opV28aPvt7XQx1krDaYm82PZueuAEBvZMOx-Zu0Mvt3THoDSKeLORL~06AVt9NGjnXezXZp7eht3UUwxGIHme8HfI3pIxTAEDlf8FyZEtjusPMSaC6I5w7hbtaIqq6zk4MGkUu3CKkeTyf~GWgVR4HQeQ24~bZoOadPKuwrmTz~QoiTOsu7i2EjH~y5usJcZkcPNAGabBvTR9U4LqeQxSujztJE-DMpIHy4j5u--w9rjhKG5CvAY5wvbmo4khfnyIeKeLCU0A-fxJwLnZ1sA-aQtDaXwMVJDLgs4mLrtDmft3Ath0QL3C83MxqDwh5deZUl3MOIyWL3A__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Metastasis of MM cells within SCID-hu mice. SCID-hu mice were treated with irradiation (400 cGy), injected directly into the marrow cavity of the left fetal human bone implant with 5 × 104 ARH-77 MM cells, and killed 12 weeks later. H&E (original magnification × 100 [A] and × 400 [B]) and immunoperoxidase staining with anti-κ Ig Ab (original magnification × 100 [C] and × 1,000 [D]) of the right-sided human fetal bone marrow implant is shown.
Mediastinum (original magnification × 40 [E]) and murine vertebral BM (original magnification × 400 [F ]) were also stained with H&E.
