American Society of Hematology

Fig. 2.

Time- and dose-dependent growth of tumor cells in fetal bone implants. ARH-77 MM cells (1 × 104 or 5 × 104) or PBS was injected directly into the marrow cavity of the left fetal human bone implant of previously irradiated (400 cGy) SCID-hu mice. Mice were killed 4, 8, and 12 weeks later, and macroscopic sections of left human bone implants were stained with H&E.

Time- and dose-dependent growth of tumor cells in fetal bone implants. ARH-77 MM cells (1 × 10⁴ or 5 × 10⁴) or PBS was injected directly into the marrow cavity of the left fetal human bone implant of previously irradiated (400 cGy) SCID-hu mice. Mice were killed 4, 8, and 12 weeks later, and macroscopic sections of left human bone implants were stained with H&E.

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