American Society of Hematology

Fig. 8.

$Fig. 8. Survival of irradiated BALB/c hosts receiving 2.5 × 106 C57BL/Ka bone marrow cells plus blood mononuclear cells from C57BL/Ka donors. In (A), hosts received bone marrow (BM) cells plus 0.25, 0.5, or 1.25 × 106 unfractionated blood mononuclear cells or low-density cells from donors receiving G-CSF. There were 10 to 12 mice in each group. In (B), hosts received marrow cells alone or with 0.25 or 0.5 × 106 mononuclear cells from untreated donors or marrow cells with 0.25, 0.5, or 1.25 × 106 mononuclear cells from donors receiving G-CSF. There were 10 to 12 mice in each group. In (C), hosts received marrow cells plus 0.1 to 0.25 × 106 purified CD4+ and CD8+ T cells from untreated donors (G−M−B− PBL) or 0.1 to 0.25 × 106 purified CD4+ and CD8+ T cells from G-CSF–treated donors (G−M−B− MOB-PBC). There were 10 mice in each group.$

Survival of irradiated BALB/c hosts receiving 2.5 × 10⁶ C57BL/Ka bone marrow cells plus blood mononuclear cells from C57BL/Ka donors. In (A), hosts received bone marrow (BM) cells plus 0.25, 0.5, or 1.25 × 10⁶ unfractionated blood mononuclear cells or low-density cells from donors receiving G-CSF. There were 10 to 12 mice in each group. In (B), hosts received marrow cells alone or with 0.25 or 0.5 × 10⁶ mononuclear cells from untreated donors or marrow cells with 0.25, 0.5, or 1.25 × 10⁶ mononuclear cells from donors receiving G-CSF. There were 10 to 12 mice in each group. In (C), hosts received marrow cells plus 0.1 to 0.25 × 10⁶ purified CD4⁺ and CD8⁺ T cells from untreated donors (G⁻M⁻B⁻ PBL) or 0.1 to 0.25 × 10⁶ purified CD4⁺ and CD8⁺ T cells from G-CSF–treated donors (G⁻M⁻B⁻ MOB-PBC). There were 10 mice in each group.

This Feature Is Available To Subscribers Only