EBV types and variants in lymphadenopathy lesions and lymphomas. Representative lymphadenopathy lesions harboring EBV type 1 (no. 17) or EBV types 1 and 2 (no. 24), and lymphoma lesions harboring EBV type 2 (no. 33) or EBV type 1 (no. 47) are shown in (A) and (B). The amplified EBNA2 products were visualized in ethidium bromide–stained acrylamide gels and detected with a radiolabeled probe that detects EBV types 1 and 2 (A); the amplified EBNA 3C products from the same samples were visualized in ethidium bromide–stained gels and detected using two different radiolabeled probes specific for EBV types 1 and 2, respectively (B). (C) LMP1 variant analysis of the same lesions. Two different LMP1 variants were detected in each lymphadenopathy lesion, while a single LMP1 variant was detected in lymphoma samples. Lane “mix” contained a mixture of five amplified LMP1 products, containing 4, 5, 6, or 7 repeats, or 5 repeats (5) with the 15-bp insertion.