Fig. 2.
Fig. 2. Comparison of biological activities between mOSM and mLIF. (A) Inhibition of [3H] thymidine uptake in mouse M1 myeloid leukemia cells by mOSM (•) and mLIF (○). (B through D) Growth stimulation of mouse myeloid DA1a cells (B), a Ba/F3 transfectant expressing gp130 and LIFRβ (C), and a Ba/F3 expressing gp130 alone (D). As a control in (D), various concentrations of human IL-6 were added in the presence of 100 ng/mL of soluble human IL-6 receptor α subunit (open triangles with broken line). Data are averages of duplicate measurements.

Comparison of biological activities between mOSM and mLIF. (A) Inhibition of [3H] thymidine uptake in mouse M1 myeloid leukemia cells by mOSM (•) and mLIF (○). (B through D) Growth stimulation of mouse myeloid DA1a cells (B), a Ba/F3 transfectant expressing gp130 and LIFRβ (C), and a Ba/F3 expressing gp130 alone (D). As a control in (D), various concentrations of human IL-6 were added in the presence of 100 ng/mL of soluble human IL-6 receptor α subunit (open triangles with broken line). Data are averages of duplicate measurements.

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