American Society of Hematology

Fig. 1.

$Fig. 1. Transplantation of NOD/SCID mice with freshly isolated human BM or BM cultured on pre-established allogeneic stroma for 1 or 2 weeks. Mice were transplanted with the indicated number of cells. After 4 to 5 weeks, human cell engraftment of the murine BM was estimated by Southern blot. The extent of human cell engraftment was determined by comparing hybridization in the sample lines with the control human/mouse mixtures using densitometric methods. S, cells from suspension culture fraction only were injected.$

Transplantation of NOD/SCID mice with freshly isolated human BM or BM cultured on pre-established allogeneic stroma for 1 or 2 weeks. Mice were transplanted with the indicated number of cells. After 4 to 5 weeks, human cell engraftment of the murine BM was estimated by Southern blot. The extent of human cell engraftment was determined by comparing hybridization in the sample lines with the control human/mouse mixtures using densitometric methods. S, cells from suspension culture fraction only were injected.

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