Fig. 7.
Fig. 7. Correlation of es nucleoside transporter expression and the sensitivity of cells to araC. Shown is a plot of data obtained with leukemia cells from AML patient H.M. (▪), ALL patient T.Z. (♦), and acute leukemia cell lines OCI/AML-2 (▴) and CEM (•). Chemosensitivity is shown as the log IC50 for araC in a 72-hour MTT assay (Fig 1), and es expression as the log Bmax for 5-(Sx8)-F binding, determined from flow cytometric measurements (Fig 2). P = .047; r = .95.

Correlation of es nucleoside transporter expression and the sensitivity of cells to araC. Shown is a plot of data obtained with leukemia cells from AML patient H.M. (▪), ALL patient T.Z. (♦), and acute leukemia cell lines OCI/AML-2 (▴) and CEM (•). Chemosensitivity is shown as the log IC50 for araC in a 72-hour MTT assay (Fig 1), and es expression as the log Bmax for 5-(Sx8)-F binding, determined from flow cytometric measurements (Fig 2). P = .047; r = .95.

Close Modal

or Create an Account

Close Modal
Close Modal