Fig. 5.
![Fig. 5. Displacement analysis of recombinant toxins. In (A), U937 cells (4.5 × 106/well) were incubated with [125I]–GM-CSF and the indicated concentrations of GM-CSF (▪), GM-CSF–PE38KDEL (○), or DT388–GM-CSF (▵). In (B), HUT-102 cells (8 × 105/well) were incubated with [125I] — anti-TFR–IgG and the indicated concentrations of anti-TFR–IgG (▪), anti-TFR(Fv)–PE38KDEL (○), or DT388–anti-TFR(Fv) (▴). The cells were harvested and counted as in Fig 3.](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/90/1/10.1182_blood.v90.1.252/5/bl_0029f5.jpeg?Expires=1722791987&Signature=jLKIVevKFJnyg0vNFOLCF8SufUN7Cak9aRE8BF5xAJgtQl9YH1XG52DlQbwx9Px1PIZrZyLBXIRascKpjGwk6XQSHok4ybyDbcplanxFR4rjxdHjskrBkyqExiRu677-RY6PjM-9L6LAK3GN3AkYKJUdq9Wu6ld~ShZZ21xmewx7EdWNA43NfeW0d7H6LU~q4sjb~lvUwXO2uRSMRZaRwMIAyoH22gECoe9GXcdabI~Em37CpsWDPR2Whtu0b5lO-CpRo~WXDNpG-apxpKeUIFpnY6zEBIPXg~hKu0V-SKeAK8ZHXp9~VClYCNBWBK0HsJJxrEwQJNNq9~65dRFLCA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Displacement analysis of recombinant toxins. In (A), U937 cells (4.5 × 106/well) were incubated with [125I]–GM-CSF and the indicated concentrations of GM-CSF (▪), GM-CSF–PE38KDEL (○), or DT388–GM-CSF (▵). In (B), HUT-102 cells (8 × 105/well) were incubated with [125I] — anti-TFR–IgG and the indicated concentrations of anti-TFR–IgG (▪), anti-TFR(Fv)–PE38KDEL (○), or DT388–anti-TFR(Fv) (▴). The cells were harvested and counted as in Fig 3.
