Fig. 2.
Fig. 2. Cytotoxicity and specificity of GM-CSF toxins on target cells. The colon lines SW403 (A) and LS174T (B) were incubated with GM-CSF–PE38KDEL and DT388–GM-CSF was incubated with the leukemia lines HL60 (C) and U937 (D) in the presence (•, ▴) or absence (○, ▵) of 5 μg/mL of GM-CSF. The cells were pulsed with [3H]-leucine and harvested, and the leucine incorporation was determined.

Cytotoxicity and specificity of GM-CSF toxins on target cells. The colon lines SW403 (A) and LS174T (B) were incubated with GM-CSF–PE38KDEL and DT388–GM-CSF was incubated with the leukemia lines HL60 (C) and U937 (D) in the presence (•, ▴) or absence (○, ▵) of 5 μg/mL of GM-CSF. The cells were pulsed with [3H]-leucine and harvested, and the leucine incorporation was determined.

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