Inhibition of acid β-glucosidase activity of recombinant normal (×) and N370S (+) enzymes expressed in the baculovirus system and alglucerase (•). Similar inhibitory profiles were obtained with the recombinant and placental acid β-glucosidase when incubated with case 2 serum. The recombinant N370S acid β-glucosidase had a similar activity profile to the normal acid β-glucosidase with non-immune sera (Fig 1).