Systolic blood pressure (in mm Hg), hematocrit (in percent), and urinary excretion of NOx⁻ (in mmol/mmol Cr) in 10-week-old rats at the end of study. Data are the mean ± SD. sBP, systolic blood pressure; Cr, creatinine. Group 1, control; group 2, isosorbide dinitrate; group 3, L-NAME; group 4, L-NAME plus L-arginine. (a) P < .005 versus group 4, P < .001 versus group 3; (b) P < .001 versus other groups; (c) P < .005 versus group 1; (d) P < .001 versus other groups; (e) P < .05 versus group 4, P < .001 versus groups 1 and 2; (f) P < .001 versus other groups; (g) P < .01 versus group 1.