Phenotypic diversity associated with the JAK2 V617F tyrosine kinase mutation might arise from a combination of the particular myeloid progenitor compartment that is affected and specific secondary mutations that occur during clonal evolution.

Phenotypic diversity associated with theJAK2V617F tyrosine kinase mutation might arise from a combination of the particular myeloid progenitor compartment that is affected and specific secondary mutations that occur during clonal evolution.

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