Inhibition of RGS16 expression in MO7e cells. MO7e cells were transduced with pRRL-SCR (control) or with pRRL-SEQ15 or with pRRL-SEQ24. (A) GFP⁺ cells were sorted and analyzed by quantitative RT-PCR for RGS16 expression. (B) SDF-1–induced migration of MO7e cell lines. MO7e pRRL-SCR (control) and MO7e pRRL-SEQ24 migrated in response to 300 ng/mL SDF-1. The percentage represents the proportion of migrated cells compared with input cells. The graph shows the mean ± SD of 4 independent experiments performed in duplicate. *P < .01