DAPI-banding analysis of HPV16 E711-20–specific CTL A9 and its hTERT-transduced counterpart CTL A9-TN. (A) DAPI-banded karyogram of a representative metaphase (n = 13) derived from untransduced A9, indicating a normal 46, XY karyotype. (B) DAPI-banded karyogram of a representative metaphase (n = 10) derived from A9-TN at 7 months after hTERT transduction, showing structural damage of chromosome arms 7q, 8q, and 10p (arrows) and rearrangements involving chromosomes 7, 15, 16, and 20 (asterisks). M indicates marker, unidentified chromosomes, or chromosome parts.