Thromboelastograms showing polymerization and tPA-mediated lysis of fibrinogen 1 or fibrinogen 2. Reaction mixtures contained fibrinogen (7 mg/mL) and lys-plasminogen (2.0 μM). Thrombin (2 U/mL, final) and tPA (0.93 nM, final) were added to initiate the reactions. (A) Fibrinogen 1. (B) Fibrinogen 2.