Figure 2.
Figure 2. EPCR immunostaining. (A) EPCR staining is readily detected on the giant trophoblasts in (i) Procr+/+ and (ii) ProcrLox embryos at E9.5, whereas no EPCR is observed on the giant trophoblast cells of the (iii) Procr –/–Tek+ embryo. Fluorescein identifies EPCR antigen. (B) Immunohistochemical detection of EPCR in thymus, heart, kidney, and lung in Procr +/+ and ProcrLox mice. Brown horseradish peroxidase reaction product identifies EPCR antigen. EPCR is absent in ProcrLox mice from all large-vessel endothelium. gc indicates trophoblast giant cell; ys, yolk sac; and dc, decidual cell. Original magnification for all panels, × 200.

EPCR immunostaining. (A) EPCR staining is readily detected on the giant trophoblasts in (i) Procr+/+ and (ii) ProcrLox embryos at E9.5, whereas no EPCR is observed on the giant trophoblast cells of the (iii) Procr–/–Tek+ embryo. Fluorescein identifies EPCR antigen. (B) Immunohistochemical detection of EPCR in thymus, heart, kidney, and lung in Procr+/+ and ProcrLox mice. Brown horseradish peroxidase reaction product identifies EPCR antigen. EPCR is absent in ProcrLox mice from all large-vessel endothelium. gc indicates trophoblast giant cell; ys, yolk sac; and dc, decidual cell. Original magnification for all panels, × 200.

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