CXCR5^-/- T cells fail to migrate to B-cell follicles. Immunohistology of cryostat sections from dLNs of mice (F1; Balb/c × 129SV) immunized with OVA plus CT that had received lymphocytes from CXCR5^+/+DO11.10 (mixed Balb/c × 129SV background; A) or CXCR5^-/-DO11.10 (mixed Balb/c × 129SV background; B) mice. At the time points indicated animals were killed and LN sections were stained with KJ1-26 (red) and anti-B220 (blue) to identify transferred cells and the B-cell follicle, respectively. A representative set of data from 2 to 4 independent experiments using 2 mice at each time point is shown.