(in List et al). Flow cytometry forward (X axis) versus side (Y axis) light scatter histograms of normal bone marrow cells and marrow cells from a patient with RCMD.

The histogram from the patient shows that glycophorin A+ erythroid precursors (red) are larger in MDS (greater forward light scatter), corresponding to megaloblastic erythropoiesis (lymphocytes painted green as a reference). Note differences between light scatter properties of normal myeloid precursors and those of the MDS patient.

Color key: Red: glycophorin A; Blue: CD14; Green: CD45++ lymphocytes; Gray: CD45+ myeloid precursors

Courtesy of Dr. Anna Porwit-MacDonald, Karolinska University Hospital