Figure 1.
Visual overview of posttransplant IR in terms of time and graft source. Comprehensive IR data are summarized in supplemental Table 2. (A-B) ALC and CD20+ B- cell, CD4+CD45RA+ T-cell, and NK-cell counts (expressed as CD3−CD56+ and CD16+CD57−) were significantly higher during the early phase in all UCB recipients (all P < .001). In contrast to NK cells, the observation of CD8+ T-cell recovery was delayed in UCB recipients compared with that in BM and PBSC recipients. However, CD4+ T-cell expansion was temporally confirmed in memory T-cell and effector T-cell subsets in UCB recipients, and the overall difference in graft source–related IR gradually decreased over time.

Visual overview of posttransplant IR in terms of time and graft source. Comprehensive IR data are summarized in supplemental Table 2. (A-B) ALC and CD20+ B- cell, CD4+CD45RA+ T-cell, and NK-cell counts (expressed as CD3CD56+ and CD16+CD57) were significantly higher during the early phase in all UCB recipients (all P < .001). In contrast to NK cells, the observation of CD8+ T-cell recovery was delayed in UCB recipients compared with that in BM and PBSC recipients. However, CD4+ T-cell expansion was temporally confirmed in memory T-cell and effector T-cell subsets in UCB recipients, and the overall difference in graft source–related IR gradually decreased over time.

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