Figure 2.
Figure 2. Recipients of G-PB grafts have faster T-cell reconstitution and thymopoiesis than BM graft recipients with more naive and TREC+ T cells. The proportions of CD4+ (A) and CD8+ (B) T cells with naive, central memory, effector memory, and terminal effector memory phenotype were determined by flow cytometry, as previously described,12 in blood samples obtained at 1, 3, 6, 12, and 24 months posttransplant from recipients of BM or G-PB grafts. Numbers of TREC+ CD4+ T cells (C) and TREC+ CD8+ T cells (D) per milliliter. (E) Percentages of TREC+ CD4+ naive T cells and TREC+ CD8+ naive T cells among recipients of BM or G-PB grafts. ***P < .001.

Recipients of G-PB grafts have faster T-cell reconstitution and thymopoiesis than BM graft recipients with more naive and TREC+ T cells. The proportions of CD4+ (A) and CD8+ (B) T cells with naive, central memory, effector memory, and terminal effector memory phenotype were determined by flow cytometry, as previously described,12  in blood samples obtained at 1, 3, 6, 12, and 24 months posttransplant from recipients of BM or G-PB grafts. Numbers of TREC+ CD4+ T cells (C) and TREC+ CD8+ T cells (D) per milliliter. (E) Percentages of TREC+ CD4+ naive T cells and TREC+ CD8+ naive T cells among recipients of BM or G-PB grafts. ***P < .001.

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