Figure 8.
DWJM affects gene expression profile of UCB-derived CD34+cells. (A) RNAseq analysis. Heat map showing significantly up- and downregulated genes in UCB CD34+ cells cultured in DWJM or in suspension (control). (B) qPCR verification of 5 genes (CD41, CXCL8, CXCR4, GATA2, VWF) that were identified by RNAseq. (C) Genes influenced by DWJM. (i) Upregulated genes by DWJM. (ii) Downregulated genes by DWJM. CD34+ cells cultured in the absence of DWJM served as the baseline. *Statistically significant. NK, natural killer.

DWJM affects gene expression profile of UCB-derived CD34+cells. (A) RNAseq analysis. Heat map showing significantly up- and downregulated genes in UCB CD34+ cells cultured in DWJM or in suspension (control). (B) qPCR verification of 5 genes (CD41, CXCL8, CXCR4, GATA2, VWF) that were identified by RNAseq. (C) Genes influenced by DWJM. (i) Upregulated genes by DWJM. (ii) Downregulated genes by DWJM. CD34+ cells cultured in the absence of DWJM served as the baseline. *Statistically significant. NK, natural killer.

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