GM-CSF and IL-3 rescue cell survival. (A) Growth curve of MV4;11 cells treated with crenolanib ± the indicated cytokine (n = 3). Percent apoptosis by Annexin-V staining (B) and proliferation index of live cells by dye dilution (C) after 72 hours of treatment of MV4;11 cells with crenolanib ± the indicated cytokine (n = 3). (D) Growth curve of MV4;11 cells treated with crenolanib ± the indicated cytokine for 3 days. Cells were replated in fresh media without treatments on day 3. DMSO-treated control diluted 1:4 to normalize for cell density (n = 3). Error bars represent SEM. **P < .01; ***P < .001; ****P < .0001. Cren10, crenolanib 10 nM; ns, not significant.