Figure 6.
Figure 6. New LSC detection in ICN-1 mice. HSC markers were used to detect leukemic HSC/HPC cells in the BM of ICN-1 mice. GFP+Lin−IL7-R−CD34+/−c-Kit+ Sca-1+ (L-LSK) cells were detected in all ICN-1 leukemic mice derived from 5 different populations (HSC1 [A], HSC2 [B], HPC1 [C], HPC2 [D], and HPC3 [E]).

New LSC detection in ICN-1 mice. HSC markers were used to detect leukemic HSC/HPC cells in the BM of ICN-1 mice. GFP+LinIL7-RCD34+/−c-Kit+ Sca-1+ (L-LSK) cells were detected in all ICN-1 leukemic mice derived from 5 different populations (HSC1 [A], HSC2 [B], HPC1 [C], HPC2 [D], and HPC3 [E]).

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