Integration of methylation and gene expression profiles of HCL and post-GC B cells. Scatter plot on the differentially methylated or expressed genes (q value < 0.05; absolute difference in average M-values > 1.0 for methylation, and absolute log₂ fold change >1.0 for gene expression). Δ of M-value is represented on the x-axis, whereas the y-axis represents log₂ fold change in gene expression. Negatively correlated genes are labeled and highlighted in blue (hypermethylated and underexpressed) or in red (hypomethylated and overexpressed), whereas positively correlated genes are not labeled and are represented in light green. The ρ and P values correspond to Pearson’s correlation for methylation and GEP fold changes.