Outcome of 1405 patients in the iBFM cohort with IR cytogenetics classified according to their CNA profile. (A-B) Kaplan-Meier survival curves (A) and forest plot (B) depicting the hazard ratio and 95% confidence interval from univariate Cox regression models comparing the EFS for group B (CYTO-IR/CNA-IR and CYTO-IR/CNA-PR) vs group A (CYTO-IR/CNA-GR). Patients in the Israeli National and Sweden studies were excluded from the forest plot, as no event occurred in group B.