HMCLs with abnormalities in the TP53 gene are highly sensitive to MV. Cells (25 000 in 200 μL) were incubated with MV-GFP (MOI = 1) for 4 days, and GFP expression (Fl1) was assessed by flow cytometry. The data represent the means of at least 3 independent experiments in 37 cell lines (each point represents 1 cell line). (A) Results were analyzed according to GFP expression, CD46 expression, and cell death. CD46 expression and cell death were assessed respectively by fluorescence (MFIR, or specific staining over control staining) and altered morphology (reduced FSC and increased SSC) using flow cytometry. The statistical analyses were performed using the Spearman test. (B-D) Results were analyzed according to TP53 status, 14q32 translocations, and RAS status, respectively. 14q32 translocations are indicated by their respective deregulated gene (MAF includes c-MAF and MAFB).²⁹  Statistical analyses were performed using the Mann-Whitney U test.