Identification of high-confidence SNVs in Mb1-CreΔPB mouse leukemias. (A-C) SNVs identified by 2 different variant caller methods, Strelka and Mutect, were combined, and overlapping SNVs were classified as high-confidence SNVs. (D) Classification of high-confidence SNVs for effect. Graph shows the number of SNVs classified according to effect. (E) Predicted biological effect of the high-confidence SNVs classified as having moderate and high effect. (F). Venn diagram showing the overlap among high-confidence SNVs identified in the 3 individual mouse leukemias.