Comparison of findings for MYD88^WTand MYD88^MUTWM. Comparison of somatic mutation frequencies between MYD88^WT and MYD88^MUT WM patients. (A) Data for mutation frequencies for 53 MYD88^MUT WM patients were acquired from our previous whole genome sequencing results, using high-quality somatic variants supported by at least 3 reads.^10,11  (B) Kaplan-Meier curves for overall survival from time of diagnosis for WM patients with MYD88^MUT, and MYD88^WT with and without DDR mutations (log-rank P < .0001).