Subclone frequencies specified for individual chromosomes. Frequency of cytogenetic aberrations, sorted by main clone (blue), main clone plus subclone within a single chromosome (green), and subclone (red) by disease entity and stage. P values denote a significant trend of increased or decreased overall frequency of the respective cytogenetic aberration in the PC-AL or PC–non-AL group, respectively. Only P values significant (P ≤ .05) after adjustment for multiple testing are provided. *P value for deletion of 17p refers to a shift in the subclone/main clone ratio along the progression of plasma cell dyscrasia (P = .013 before adjustment; P = .15 after adjustment for multiple testing).