Lymphocyte predominant Hodgkin disease.

(A,E) Radioactive in situ hybridization with probes specific for Igγ and Igλ mRNA, respectively. The L&H cells (white arrows) are positive with an intensity between that seen in plasma cells and B cells (black arrows). (B-D,F) Immunostaining for Igγ, -μ, -δ, and -λ, using a avidin-biotin-peroxidase method. The L&H cells display a strong labeling.