Distribution of differentiated cell outputs of defined phenotypes of lin^– CD34⁺ CB cells. (A) General experimental design. (B-C) Number of input cells in each of the 8 CD34⁺ input phenotypes analyzed with the output activities shown. Hematopoietic stem cells (HSC): CD34⁺CD38^–CD45RA^–CD90⁺CD49f⁺. MPPs: CD34⁺CD38^–CD45RA^–CD90^–CD49f^–. LMPPs: CD34⁺CD38^–CD10^–CD45RA⁺. MLPs: CD34⁺CD38^–CD10⁺CD45RA⁺. CMPs: CD34⁺CD38⁺CD10^–CD135⁺CD45RA^–. MEPs: CD34⁺CD38⁺CD10^–CD135^–CD45RA^–. GMPs: CD34⁺CD38⁺CD10^–CD135⁺CD45RA⁺. Pre–B/NKs: CD34⁺CD38⁺CD10⁺CD45RA⁺. The number of input cells (n) within each phenotype is also shown. Legends indicate the combinations of lineages observed visually in (B) MC assays or (C) according to flow cytometry in STCs. (B) Number of 6 types of clonogenic cells identified in single-cell MC assays of 660 randomly selected, index-sorted lin^–CD34⁺ CB cells (3 experiments). (C) Number of cells with indicated cellular outputs assessed in 3-week single-cell STC assays of 480 randomly selected, index-sorted lin^–CD34⁺ CB cells (2 experiments).