Immunologic prognostic biomarkers in intensively treated AML patients (HD-cytarabine–based induction treatment; n = 59). (A) Volcano plot of the HRs for an EFS incident of immune cells and their immunophenotypes and PB and BM laboratory values. Variables increasing the risk for an EFS event have a positive log10 HR and deviate to the right side of the plot. Parameters with a negative log10 HR diverge to the left. Survival plot of the proportion of CD68⁺ monocytes expressing pSTAT1⁺cMAF⁻ (M1-like monocytes) (B) and helper T cells expressing FOXP3⁺ (%, regulatory T cells) (C). Covariates were divided into tertiles, and the highest 2 subgroups were combined. A forest plot displaying the HR and 95% CI of the categorized proportion of M1-like monocytes (D) and Tregs (E) in univariate and combined with another essential clinical biomarker (Cox regression analysis).