Diagram of the principle features of the mutated CALR–TpoR interaction leading to cell surface transport from the ER, TpoR activation, and signal transduction. See Figure 6E in the article by Pecquet et al that begins on page 2669.
Diagram of the principle features of the mutated CALR–TpoR interaction leading to cell surface transport from the ER, TpoR activation, and signal transduction. See Figure 6E in the article by Pecquet et al that begins on page 2669.