Superior PFS and OS in patients with aggressive NHL who achieved CR and had high peak IL-7 concentrations. Kaplan-Meier estimates of PFS (A) and OS (B) in patients with aggressive NHL who achieved CR and had serum peak IL-7 concentration above the median (red) compared with those who had serum peak IL-7 concentration below or equal to the median (blue). The numbers of patients at risk at 6-month intervals are indicated. Log-rank tests were used to compare between-group differences in survival probabilities. (C) Serum IL-7 concentrations in patients who remained in CR (red) and in those who subsequently relapsed (blue; P = .05 for the difference in the IL-7 area under the curve from peak to day 28 between the groups). Adjusted P values were calculated by using the Wilcoxon rank-sum test.