Timeline showing a selection of hematopoietic clonal approaches. Clonal approaches illustrated include chromosome characterization, hematopoietic colony assays, transplantation studies, and sequencing-based techniques. Major milestones in the development of these approaches are shown in the timeline.^{15,19,20,23,38,40,41,106-110}  G&T-seq, genome and transcriptome sequencing; Trio-seq, single-cell triple omics sequencing.