American Society of Hematology

Figure 5.

$Figure 5. Differential effect of BFA on TF expression in PAMP-stimulated monocytes. (A) Pairwise representation of BFA treatment on procoagulant responses after PGN (10 µg/mL) or LPS (1 µg/mL) stimulation. BFA increases the fraction of procoagulant monocytes (TF+CD14+) after LPS stimulation but decreases procoagulant monocytes after PGN stimulation. (B) Pairwise representation of the differential effect of BFA on monocyte TF fluorescence intensity after PGN or LPS stimulation. (C) Pairwise comparison of normalized changes in PAMP-induced monocyte TF intensity (TF geometric mean BFA+/TF geometric mean BFA–) in the studied cohort (n = 26). Differences between paired groups were analyzed by using ratio-paired Student t tests (panels A and B) or RM 1-way ANOVA (panel C).$

Differential effect of BFA on TF expression in PAMP-stimulated monocytes. (A) Pairwise representation of BFA treatment on procoagulant responses after PGN (10 µg/mL) or LPS (1 µg/mL) stimulation. BFA increases the fraction of procoagulant monocytes (TF⁺CD14⁺) after LPS stimulation but decreases procoagulant monocytes after PGN stimulation. (B) Pairwise representation of the differential effect of BFA on monocyte TF fluorescence intensity after PGN or LPS stimulation. (C) Pairwise comparison of normalized changes in PAMP-induced monocyte TF intensity (TF geometric mean BFA⁺/TF geometric mean BFA^–) in the studied cohort (n = 26). Differences between paired groups were analyzed by using ratio-paired Student t tests (panels A and B) or RM 1-way ANOVA (panel C).

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