Association between CLEC4M VNTR variant and FVIII PK parameters. Analysis of the association between the CLEC4M VNTR variant and FVIII PK or VWF levels by 1-way ANOVA. (A) Association between the CLEC4M VNTR variant and FVIII clearance. (B) Association between the CLEC4M VNTR variant and FVIII elimination rate constant (k). (C) Association between the CLEC4M VNTR variant and FVIII half-life. (D) Association between the CLEC4M VNTR variant and FVIII AUC. (E) Association between the CLEC4M VNTR variant and VWF:Ag. (F) Association between the CLEC4M VNTR variant and VWFpp/VWF:Ag. *P ≤ .05.