Reductions in the sum of the products of perpendicular diameters of target lymph nodes. In patients with (A) treatment-naive or (B) relapsed/refractory CLL/SLL; (C) kinetics of lymphocytosis. Data indicate median percentage change in lymphocyte counts and 95% CIs. ALC, absolute lymphocyte count; SD, stable disease; SPD, sum of the products of lymph node diameters as assessed by computed tomography scan.