Figure 2.
Figure 2. Recurrent gene mutations, VAF of mutations, and gene expression in MPN cohort. Thirty-five of 87 myeloid-related genes (Figure 1C; supplemental Table 7) with the highest mutation frequency within the cohort are depicted (left panel). Mutations are sorted as described in Figure 1C and colored by diagnosis. VAF for each mutation colored by mutation type (middle panel). Gene-expression values were reported for each patient as fragments per kilobase per million reads (FPKM) (supplemental Table 12) (right panel). Expression values are plotted as log2(FPKM). Patients with a mutation in the respective gene are shown as vertical bars. Numbers indicate the minimum and maximum expression values.

Recurrent gene mutations, VAF of mutations, and gene expression in MPN cohort. Thirty-five of 87 myeloid-related genes (Figure 1C; supplemental Table 7) with the highest mutation frequency within the cohort are depicted (left panel). Mutations are sorted as described in Figure 1C and colored by diagnosis. VAF for each mutation colored by mutation type (middle panel). Gene-expression values were reported for each patient as fragments per kilobase per million reads (FPKM) (supplemental Table 12) (right panel). Expression values are plotted as log2(FPKM). Patients with a mutation in the respective gene are shown as vertical bars. Numbers indicate the minimum and maximum expression values.

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